Pain relief and euphoria are achieved in opioid use when the drug crosses the blood-brain barrier to access the central nervous system (Schaefer, Tome & Davis, 2017). While the user feels a temporary sense of well-being, persistent use creates a dysregulation of dopamine transmission, and a co-occurring impairment in the frontal brain regions impacts cognition and function (Tolomeo, Gray, Matthews, Steel & Baldacchino, 2016). In addition to the cognitive and functional changes, imaging has documented volume loss in the brain associated with long-term use of opioids. Even several years into recovery, people who abused opioids continue to experience cognitive impairments, indicating the dysfunction is long-term and not due solely to the presence of the drug (Ersche, Clark, London, Robbins & Sahakian, 2006).
In some studies, measures of neurocognitive function have shown that people with opioid dependence demonstrate impairments in the areas of memory, attention, spatial planning, and executive functions. There is also evidence that information processing speed is negatively impacted by chronic opioid use, causing difficulty with adjusting to new situations or learning new information
Originally Posted by ChiliConCarnage:
I thought I remembered summer like this..not sure why he'd want or need to be selling them though.
Maybe the bounty story was actually true as well. If so, Payton would have needed money to pay the bounties. Coaches don't generally make exorbitant salaries like some players do, so he might have been financing his own program while simultaneously lining his pockets. [Reply]