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Nolan Ryan threw 235 pitches in a game against the Boston Red Sox on June 14, 1974, which is considered the modern record for the most pitches in an extra-inning game.
In MLB, pitchers are limited to 110 pitches per game or per day. If a pitcher reaches the limit while facing a batter, they can continue pitching until the batter reaches base, is retired, or the third out is recorded.
I knew about the Nolan Ryan, 235 pitch thing, but I've never heard of this 110 limit for pitchers. [Reply]